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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
06/12/2019 |
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Actualizado : |
05/09/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
BERRO, I.; LADO, B.; NALIN, R.S.; QUINCKE, M.; GUTIÉRREZ, L. |
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Afiliación : |
Dep. of Agronomy, Univ. of Wisconsin, Madison, USA.; Facultad de Agronomía, Univ. de la República, Montevideo, Uruguay.; Dep. of Agronomy, Univ. of Wisconsin, Madison, USA.; MARTIN CONRADO QUINCKE WALDEN, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Dep. of Agronomy, Univ. of Wisconsin, Madison, USA./ Facultad de Agronomía, Univ. de la República, Montevideo, Uruguay. |
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Título : |
Training population optimization for genomic selection. |
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Fecha de publicación : |
2019 |
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Fuente / Imprenta : |
Plant Genome, November 2019, Volume 12, Issue 3, Article number 190028. OPEN ACCESS. DOI: https://doi.org/10.3835/plantgenome2019.04.0028 |
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DOI : |
10.3835/plantgenome2019.04.0028 |
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Idioma : |
Inglés |
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Notas : |
Article histoty: Received 1 Apr. 2019. /Accepted 23 Sept. 2019. |
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Contenido : |
ABSTRACT :The effectiveness of genomic selection in breeding programs depends on the phenotypic quality and depth, the
prediction model, the number and type of molecular markers, and the size and composition of the training population (TR).
Furthermore, population structure and diversity have a key role in the composition of the optimal training sets. Our goal was
to compare strategies for optimizing the TR for specific testing populations (TE). A total of 1353 wheat (Triticum aestivum
L.) and 644 rice (Oryza sativa L.) advanced lines were evaluated for grain yield in multiple environments. Several within-TR optimization
strategies were compared to identify groups of individuals with increased predictive ability. Additionally, optimization strategies
to choose individuals from the TR with higher predictive ability for a specific TE were compared. There is a benefit in considering
both the population structure and the relationship between the TR and the TE when designing an optimal TR for genomic
selection. A weighted relationship matrix with stratified sampling is the best strategy for forward predictions of quantitative traits in
populations several generations apart. Genomic selection (GS) consists of selecting individuals from a TE on the basis of genotypic values predicted from their genome-wide molecular marker scores and a statistical model adjusted with individuals that have phenotypic and genotypic information (Meuwissen et al., 2001). The group of individuals that were phenotyped and genotyped is called the TR (Heffner et al. 2009). MenosABSTRACT :The effectiveness of genomic selection in breeding programs depends on the phenotypic quality and depth, the
prediction model, the number and type of molecular markers, and the size and composition of the training population (TR).
Furthermore, population structure and diversity have a key role in the composition of the optimal training sets. Our goal was
to compare strategies for optimizing the TR for specific testing populations (TE). A total of 1353 wheat (Triticum aestivum
L.) and 644 rice (Oryza sativa L.) advanced lines were evaluated for grain yield in multiple environments. Several within-TR optimization
strategies were compared to identify groups of individuals with increased predictive ability. Additionally, optimization strategies
to choose individuals from the TR with higher predictive ability for a specific TE were compared. There is a benefit in considering
both the population structure and the relationship between the TR and the TE when designing an optimal TR for genomic
selection. A weighted relationship matrix with stratified sampling is the best strategy for forward predictions of quantitative traits in
populations several generations apart. Genomic selection (GS) consists of selecting individuals from a TE on the basis of genotypic values predicted from their genome-wide molecular marker scores and a statistical model adjusted with individuals that have phenotypic and genotypic information (Meuwissen et al., 2001). The group of individ... Presentar Todo |
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Palabras claves : |
GENOMIC SELECTION; SELECCIÓN GENÓMICA. |
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Thesagro : |
TRIGO; TRITICUM AESTIVUM. |
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Asunto categoría : |
F01 Cultivo |
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URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16707/1/The-Plant-Genome-2019-Berro-Training-Population-Optimization-for-Genomic-Selection.pdf
https://acsess.onlinelibrary.wiley.com/doi/epdf/10.3835/plantgenome2019.04.0028
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Marc : |
LEADER 02385naa a2200241 a 4500
001 1060511
005 2022-09-05
008 2019 bl uuuu u00u1 u #d
024 7 $a10.3835/plantgenome2019.04.0028$2DOI
100 1 $aBERRO, I.
245 $aTraining population optimization for genomic selection.$h[electronic resource]
260 $c2019
500 $aArticle histoty: Received 1 Apr. 2019. /Accepted 23 Sept. 2019.
520 $aABSTRACT :The effectiveness of genomic selection in breeding programs depends on the phenotypic quality and depth, the prediction model, the number and type of molecular markers, and the size and composition of the training population (TR). Furthermore, population structure and diversity have a key role in the composition of the optimal training sets. Our goal was to compare strategies for optimizing the TR for specific testing populations (TE). A total of 1353 wheat (Triticum aestivum L.) and 644 rice (Oryza sativa L.) advanced lines were evaluated for grain yield in multiple environments. Several within-TR optimization strategies were compared to identify groups of individuals with increased predictive ability. Additionally, optimization strategies to choose individuals from the TR with higher predictive ability for a specific TE were compared. There is a benefit in considering both the population structure and the relationship between the TR and the TE when designing an optimal TR for genomic selection. A weighted relationship matrix with stratified sampling is the best strategy for forward predictions of quantitative traits in populations several generations apart. Genomic selection (GS) consists of selecting individuals from a TE on the basis of genotypic values predicted from their genome-wide molecular marker scores and a statistical model adjusted with individuals that have phenotypic and genotypic information (Meuwissen et al., 2001). The group of individuals that were phenotyped and genotyped is called the TR (Heffner et al. 2009).
650 $aTRIGO
650 $aTRITICUM AESTIVUM
653 $aGENOMIC SELECTION
653 $aSELECCIÓN GENÓMICA
700 1 $aLADO, B.
700 1 $aNALIN, R.S.
700 1 $aQUINCKE, M.
700 1 $aGUTIÉRREZ, L.
773 $tPlant Genome, November 2019, Volume 12, Issue 3, Article number 190028. OPEN ACCESS. DOI: https://doi.org/10.3835/plantgenome2019.04.0028
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Registro original : |
INIA La Estanzuela (LE) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
27/01/2020 |
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Actualizado : |
27/01/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
DA CUNHA, A.L.B.; DE MEDEIROS, J.P.; RIET-CORREA, F.; GARDNER, D.; DA SILVA CHAVES, H.A.; DA SILVA FILHO, G.B.; SOUZA, F.A.L.; NETO, J.E.; MENDONÇA, F.S. |
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Afiliación : |
ANA LIZIA BRITO DA CUNHA, Universidade Federal Rural de Pernambuco (UFRPE), Recife, PE, Brazil; JULIANA PINTO DE MEDEIROS, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DALE GARDNER, Poisonous Plant Research Laboratory, Agricultural Research Service, Department of Agriculture, Logan, UT, United States; HISADORA ADVÍNCULA DA SILVA CHAVES, Laboratório de Diagnóstico Animal, Departamento de Morfologia e Fisiologia Animal (DMFA), Recife, PE, Brazil; GIVALDO BOM DA SILVA FILHO, Laboratório de Diagnóstico Animal, Departamento de Morfologia e Fisiologia Animal (DMFA), Recife, PE, Brazil; FRANCISCO DE ASSIS LEITE SOUZA, Laboratório de Diagnóstico Animal, Departamento de Morfologia e Fisiologia Animal (DMFA), Recife, PE, Brazil; JOAQUIM EVÊNCIO NETO, Laboratório de Diagnóstico Animal, Departamento de Morfologia e Fisiologia Animal (DMFA), Recife, PE, Brazil; FÁBIO DE SOUZA MENDONÇA, Laboratório de Diagnóstico Animal, Departamento de Morfologia e Fisiologia Animal (DMFA), Recife, PE, Brazil. |
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Título : |
Ipomoea brasiliana poisoning on buck reproduction. [Efeitos da intoxicação por Ipomoea brasiliana na reprodução de caprinos]. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Ciencia Rural, 2018, Volume 48, Issue 10, 2018, Article number e20180061. OPEN ACCESS. Doi: http://dx.doi.org/10.1590/0103-8478cr20180061 |
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ISSN : |
0103-8478 |
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DOI : |
10.1590/0103-8478cr20180061 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: January 29 2018 / Accepted: September 06 2018 / Revised: September 27 2018. |
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Contenido : |
ABSTRACT.
Swainsonine-containing plants comprise a group of important poisonous plants in Brazil. This research aimed to characterize both the behavioral changes related to reproduction and appearance of lesions in the reproductive system of bucks poisoned by Ipomoea brasiliana. I. brasiliana plants were collected and administered at a dose of 4g/kg (800?g swainsonine/kg) to two groups of bucks for 45 days. Goats from Group I were euthanized on the 46th day of the experiment, and goats from Group II were euthanized on the 120th day. Group III was composed of goats that did not receive I. brasiliana and were euthanized on the 120th day of the experiment. Reproductive behavioral changes were observed starting on day 20 and were characterized by an absence of courtship behavior, and Flehmen reflex, decrease or loss of libido and inability to perform mating. After 120 days, Group II goats showed no regression of the changes in their reproductive behavior or improvement of their seminal parameters. The main defects observed in the sperm of goats that consumed I. brasiliana were cytoplasmatic droplets, bent tails and detached tails. The main histopathological findings were reported in tests, with cytoplasmic vacuolization of germline and Sertoli cells, generalized impairment of spermatogonia maturation with exfoliation of degenerative cells, cell fragments, rare abnormal spermatocytes in the seminiferous lumen and disappearance of Leydig cells. Results of this study confirmed the hypothesis that I. brasiliana causes testicular degeneration in male goats.
© 2019, Universidade Federal de Santa Maria. All rights reserved.
RESUMO.
Este trabalho teve como objetivo caracterizar as mudanças comportamentais relacionadas a reprodução e lesões no sistema reprodutor de caprinos intoxicados por Ipomoea brasiliana. A planta foi coletada e administrada na dose de 4g/kg (800?g swainsonina/kg) para dois grupos de caprinos durante 45 dias. Os caprinos do Grupo I foram eutanasiados no 46º dia do experimento e os caprinos do Grupo II no 120º dia. O Grupo III foi constituído por caprinos que não receberam I. brasiliana e foram eutanasiados no 120º dia de experimento. Alterações comportamentais reprodutivas foram observadas a partir de 20 dias de experimento e consistiram em ausência do comportamento de corte, ausência de reflexo de Flehmen, diminuição ou perda de libido e incapacidade de realizar a monta natural. Após 120 dias, os caprinos do Grupo II não apresentaram regressão de alterações reprodutivas. Os principais defeitos observados no sêmen dos caprinos que consumiam I. brasiliana foram gotas citoplasmáticas, caudas dobradas e caudas destacadas. Os principais achados histopatológicos consistiram em vacuolização citoplasmática das células da linhagem germinativa e células de Sertoli; comprometimento generalizado da maturação das espermatogônias com esfoliação de células degeneradas; presença de fragmentos celulares e raros espermatócitos anormais no lúmen dos túbulos seminíferos e ausência de células de Leydig. Os resultados confirmam a hipótese de que o consumo de I. brasiliana causa degeneração testicular em caprinos. MenosABSTRACT.
Swainsonine-containing plants comprise a group of important poisonous plants in Brazil. This research aimed to characterize both the behavioral changes related to reproduction and appearance of lesions in the reproductive system of bucks poisoned by Ipomoea brasiliana. I. brasiliana plants were collected and administered at a dose of 4g/kg (800?g swainsonine/kg) to two groups of bucks for 45 days. Goats from Group I were euthanized on the 46th day of the experiment, and goats from Group II were euthanized on the 120th day. Group III was composed of goats that did not receive I. brasiliana and were euthanized on the 120th day of the experiment. Reproductive behavioral changes were observed starting on day 20 and were characterized by an absence of courtship behavior, and Flehmen reflex, decrease or loss of libido and inability to perform mating. After 120 days, Group II goats showed no regression of the changes in their reproductive behavior or improvement of their seminal parameters. The main defects observed in the sperm of goats that consumed I. brasiliana were cytoplasmatic droplets, bent tails and detached tails. The main histopathological findings were reported in tests, with cytoplasmic vacuolization of germline and Sertoli cells, generalized impairment of spermatogonia maturation with exfoliation of degenerative cells, cell fragments, rare abnormal spermatocytes in the seminiferous lumen and disappearance of Leydig cells. Results of this study confirmed the ... Presentar Todo |
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Palabras claves : |
Alcalóides; Alkaloids; Doença de depósito lisossomal; Lysosomal storage disease; Plant poisoning; Planta tóxica; PLATAFORMA SALUD ANIMAL; Ruminantes; Ruminants. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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URL : |
http://www.scielo.br/pdf/cr/v48n10/1678-4596-cr-48-10-e20180061.pdf
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Marc : |
LEADER 04472naa a2200361 a 4500
001 1060697
005 2020-01-27
008 2018 bl uuuu u00u1 u #d
022 $a0103-8478
024 7 $a10.1590/0103-8478cr20180061$2DOI
100 1 $aDA CUNHA, A.L.B.
245 $aIpomoea brasiliana poisoning on buck reproduction. [Efeitos da intoxicação por Ipomoea brasiliana na reprodução de caprinos].$h[electronic resource]
260 $c2018
500 $aArticle history: Received: January 29 2018 / Accepted: September 06 2018 / Revised: September 27 2018.
520 $aABSTRACT. Swainsonine-containing plants comprise a group of important poisonous plants in Brazil. This research aimed to characterize both the behavioral changes related to reproduction and appearance of lesions in the reproductive system of bucks poisoned by Ipomoea brasiliana. I. brasiliana plants were collected and administered at a dose of 4g/kg (800?g swainsonine/kg) to two groups of bucks for 45 days. Goats from Group I were euthanized on the 46th day of the experiment, and goats from Group II were euthanized on the 120th day. Group III was composed of goats that did not receive I. brasiliana and were euthanized on the 120th day of the experiment. Reproductive behavioral changes were observed starting on day 20 and were characterized by an absence of courtship behavior, and Flehmen reflex, decrease or loss of libido and inability to perform mating. After 120 days, Group II goats showed no regression of the changes in their reproductive behavior or improvement of their seminal parameters. The main defects observed in the sperm of goats that consumed I. brasiliana were cytoplasmatic droplets, bent tails and detached tails. The main histopathological findings were reported in tests, with cytoplasmic vacuolization of germline and Sertoli cells, generalized impairment of spermatogonia maturation with exfoliation of degenerative cells, cell fragments, rare abnormal spermatocytes in the seminiferous lumen and disappearance of Leydig cells. Results of this study confirmed the hypothesis that I. brasiliana causes testicular degeneration in male goats. © 2019, Universidade Federal de Santa Maria. All rights reserved. RESUMO. Este trabalho teve como objetivo caracterizar as mudanças comportamentais relacionadas a reprodução e lesões no sistema reprodutor de caprinos intoxicados por Ipomoea brasiliana. A planta foi coletada e administrada na dose de 4g/kg (800?g swainsonina/kg) para dois grupos de caprinos durante 45 dias. Os caprinos do Grupo I foram eutanasiados no 46º dia do experimento e os caprinos do Grupo II no 120º dia. O Grupo III foi constituído por caprinos que não receberam I. brasiliana e foram eutanasiados no 120º dia de experimento. Alterações comportamentais reprodutivas foram observadas a partir de 20 dias de experimento e consistiram em ausência do comportamento de corte, ausência de reflexo de Flehmen, diminuição ou perda de libido e incapacidade de realizar a monta natural. Após 120 dias, os caprinos do Grupo II não apresentaram regressão de alterações reprodutivas. Os principais defeitos observados no sêmen dos caprinos que consumiam I. brasiliana foram gotas citoplasmáticas, caudas dobradas e caudas destacadas. Os principais achados histopatológicos consistiram em vacuolização citoplasmática das células da linhagem germinativa e células de Sertoli; comprometimento generalizado da maturação das espermatogônias com esfoliação de células degeneradas; presença de fragmentos celulares e raros espermatócitos anormais no lúmen dos túbulos seminíferos e ausência de células de Leydig. Os resultados confirmam a hipótese de que o consumo de I. brasiliana causa degeneração testicular em caprinos.
653 $aAlcalóides
653 $aAlkaloids
653 $aDoença de depósito lisossomal
653 $aLysosomal storage disease
653 $aPlant poisoning
653 $aPlanta tóxica
653 $aPLATAFORMA SALUD ANIMAL
653 $aRuminantes
653 $aRuminants
700 1 $aDE MEDEIROS, J.P.
700 1 $aRIET-CORREA, F.
700 1 $aGARDNER, D.
700 1 $aDA SILVA CHAVES, H.A.
700 1 $aDA SILVA FILHO, G.B.
700 1 $aSOUZA, F.A.L.
700 1 $aNETO, J.E.
700 1 $aMENDONÇA, F.S.
773 $tCiencia Rural, 2018, Volume 48, Issue 10, 2018, Article number e20180061. OPEN ACCESS. Doi: http://dx.doi.org/10.1590/0103-8478cr20180061
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